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EDITECH: Biomarker discovery

Blood biomarkers discovery.

ALCEDIAG, companion tests

EDITECH: Biomarker discovery

Blood biomarkers discovery.

ALCEDIAG, companion tests

ALCEDIAG brings EDITECH, a service of biomarkers discovery based on the company experience and expertise on RNA editing.

ALCEDIAG developed EDITECH, a platform and methodology to discover and validate biomarkers based on the study of RNA editing. ALCEDIAG uses EDITECH for its own development and proposes it as a service. EDITECH enables the development of tailor-made biomarkers, designed specifically to answer the clinical question of the user. EDITECH allows the discovery of new biomarkers in no more than a few months.

This platform can be used whenever the pathology targeted is related to RNA editing modifications. Such relations have been identified so far for a large number of diseases including:

  • Neuropsychiatric diseases: depression, bipolar disorder, schizophrenia, Alzheimer’s, suicidal behavior, etc.;
  • Inflammatory diseases: Systemic Lupus Erythematosus, Aicardi Gouttiere syndrom, systemic inflammation, etc.;
  • Cancer: hepatocellular carcinoma, breast, lung, kidney, prostate cancer, metastatic melanoma, etc.

During a rapid process that lasts no more than a few months, ALCEDIAG performs a series of blood NGS analyses on a set of patients and controls, as well as network analysis. The company can then confirm the results on a discovery cohort. ALCEDIAG adapts the process to its clients’ needs, to the pathology and to the clinical question addressed.

EDITECH process - ALCEDIAG